“92 percent of drugs that pass preclinical tests, including “pivotal” animal tests, fail to proceed to the market”…”The main causes of failure are lack of effectiveness and safety problems that were not predicted by animal tests.”

– Dr. Aysha Akhtar, M.D., M.P.H

“Clinical studies take years to complete and testing a single compound can cost more than $2 billion. Meanwhile, innumerable animal lives are lost, and the process often fails to predict human responses because traditional animal models often do not accurately mimic human pathophysiology”

– Harvard University

“Each Organ-Chip mimics the functional unit of a human body organ and is created by culturing a few of that organ’s specialized cells on a clear flexible polymer about the size of a computer memory stick.”

– Animals In Science Policy Institute

“microchip organs could replace animal studies by potentially offering a more ethical disease model which can provide a greater level of insight into the efficacy and toxicology of a drug candidate.”

– Verdict Medical Devices

“Approximately 150 stroke treatments that were successful in animals have failed in clinical trials, sometimes injuring or killing patients”

– CAMARADES

“Animal models often fail to provide good ways to mimic disease or predict how drugs will work in humans, resulting in much wasted time and money while patients wait for therapies”

– NIH-wide Strategic Plan 2016-2020